Benzeneacetic acid, 3-chloro-5-fluoro-

Benzeneacetic acid, 3-chloro-5-fluoro- - Names and Identifiers

Name	3-Chloro-5-fluorophenylacetic acid
Synonyms	SALOR-INT L301000-1EA (3-chloro-5-fluorophenyl)acetate 3-CHLORO-5-FLUOROPHENYLACETIC ACID 3-Chloro-5-fluorophenylacetic acid Benzeneacetic acid, 3-chloro-5-fluoro- 2-(3-chloro-5-fluorophenyl)acetic acid
CAS	202001-00-1
InChI	InChI=1/C8H6ClFO2/c9-6-1-5(3-8(11)12)2-7(10)4-6/h1-2,4H,3H2,(H,11,12)

Benzeneacetic acid, 3-chloro-5-fluoro- - Physico-chemical Properties

Molecular Formula	C8H6ClFO2
Molar Mass	188.58
Density	1.417±0.06 g/cm3(Predicted)
Melting Point	82-87 °C
Boling Point	284.1±25.0 °C(Predicted)
Flash Point	125.6°C
Vapor Presure	0.00143mmHg at 25°C
Appearance	White crystalline powder
pKa	3.92±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.548
MDL	MFCD03788475

Benzeneacetic acid, 3-chloro-5-fluoro- - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S26/37/39 - S24/25 - Avoid contact with skin and eyes.
HS Code	29163990
Hazard Note	Irritant

Benzeneacetic acid, 3-chloro-5-fluoro- - Introduction

acid is an organic compound with the chemical formula C8H5ClFO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: acid is a colorless to yellowish solid.
-Solubility: It has low solubility in water and is more soluble in organic solvents such as ethanol and dichloromethane.
-Melting point and boiling point: Its melting point is about 68-70 ° C, and its boiling point is about 225-227 ° C.

Use:
-Chemical synthesis: acid can be used as an intermediate in organic synthesis and used to synthesize other compounds.
-Agriculture: It can also be used as an important raw material in the synthesis of pesticides.

Method:
The preparation method of acid can be realized by the following steps:
1. Phenylacetic acid reacts with thionyl chloride at high temperature to generate thionyl chloride ester. br>2. The thionyl chloride ester is reacted with fluorinated sulfoxide, phosphorus oxide and alkali catalyst at low temperature to obtain acid.

Safety Information:
-must acid have low toxicity under normal use conditions.
-In contact with skin and eyes, rinse quickly with plenty of water and seek medical help in time.
-During operation and storage, care should be taken to avoid contact with ignition sources and other flammable materials.
-Please follow the safety procedures when using, and use appropriate protective measures, such as wearing gloves and glasses.

Last Update：2024-04-10 22:29:15